Alteogen's Eylea biosimilar wins full approval from Korean regulator

Alteogen (196170) said in a filing that Korea's Ministry of Food and Drug Safety approved its Eylea biosimilar, Eyzenfy (code ALT-L9, ingredient aflibercept), on May 14, nearly 20 months after the company applied in September 2024.

The approval covers every indication the original Eylea holds in Korea: wet age-related macular degeneration, diabetic macular edema, macular edema from retinal vein occlusion, and vision loss from myopic choroidal neovascularization. The filing states Alteogen's next step is pursuing a domestic launch, without giving a date, price or distribution partner.

Unlike Alteogen's ALT-B4 licensing deals with Novartis and MSD, Eyzenfy is the company's own branded product rather than a licensed technology, so the filing carries no milestone or royalty figure. The company frames the commercial case only in general terms, as import substitution for the originator drug and a lower price point that could expand patient access.

Alteogen's FY2025 revenue of KRW 215.9 billion came almost entirely from licensing fees rather than product sales; Eyzenfy would be a rare direct product-sales line if it launches. The filing does not disclose expected sales.

215.9 billion won.

Written from the filing or the Korean-language report it cites, not translated from it. Figures against this company's own statements are computed from DART data on kstock. kstock does not issue buy, sell or hold ratings and this is not investment advice.

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